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Showing posts with label medicine. Show all posts
Showing posts with label medicine. Show all posts

Hop flowers Potentially So Cancer Drugs

Hop flowers Potentially So Cancer Drugs
Hop , a set of female flowers of the species or Strobilus hop , Humulus lupulus , used in beer mixture as it can potentially cure . According to a study published in the journal Angewandte Chemie International , hob can be used to treat diabetes , inflammation and some types of cancer .

Hops is commonly used as flavorings and stabilizers namely beer taste with bitter and sour flavors add to the beer . By adding hops to beer , beer flavor becomes stronger . A recent study found that there is a certain bitter compounds in hops that humulones , which could potentially be a cure . But that does not mean it makes the beer is also useful as a medicinal drug .

The study authors said in a release , " Excessive consumption of beer can not be recommended for better health . Humulones Only isolated , following its derivatives , which may provide health benefits . "

Researchers discover molecular configuration of compound humulones by a process called X - ray crystallography , a technique that was developed in the early 20th century . Apparently, during the brewing process , the molecules of these compounds undergo rearrangements , namely a ring structure with five carbon atoms , instead of six .

By looking at the configuration of the molecule during the brewing process , the researchers were able to determine which molecules correspond with a bitter taste in beer . As a result , they can determine the atomic arrangement is most effective in treating the disease . It is important to remember the effectiveness of compounds in treating diseases .

" Now we get the right result , what happens when hops provide a bitter taste in the beer making process to be more reasonable , " said Werner Kaminsky , researcher and professor of chemistry University of Washington . The researchers could find a way to combine these molecules with other chemicals to make drugs , such as anti - diabetic drugs . But still need further research .

Marijuana, drugs against diabetes in the future?

Marijuana, drugs against diabetes in the future?
Scientists continue to explore the possibility of cannabis , aka marijuana plants in treatment. A new study says , marijuana contains components that can help control blood sugar .

Cannabis also has a strong association with body weight. In addition to increasing appetite , cannabis could actually help a person stay slim .

Three recent studies have shown that marijuana users had a lower risk of obesity. In addition, they also have a lower risk of diabetes and the values ??of body mass index are smaller. The third advantage is obtained even if marijuana users drink more calories.

How does that happen? One reason is that marijuana users have a better carbohydrate metabolism.

"Their fasting insulin levels were also lower , and they also have a lower risk of insulin resistance ( a condition that triggers diabetes) due to the body's ability to maintain levels of normal blood sugar , "said Murray Mittleman , researchers from Harvard Medical School.

The research Mittleman it includes 4,600 men and women who participated in the National Health and Nutrition Examination Survey between 2005 to 2010 .

Of these respondents, 48 percent had smoked marijuana at least once in their lives, and 12 percent are still sucking up now .

The researchers controlled for other risk factors that affect the risk of diabetes , such as age, sex, akohol use , smoking and physical activity .

Although the risk factors considered, marijuana users have so far in fasting insulin 16 percent lower than those who had never smoked or had not smoked again. Cannabis has also been getting sucker decreased levels of insulin resistance by about 17 percent.

The fasting insulin levels and insulin resistance levels are also closely associated with the onset of diabetes and obesity type two .

The marijuana users also found to have higher levels of good cholesterol , which can protect the body against heart disease. In general, they also have a smaller tower .

Researchers do not yet fully understand the connection because the search is not case-control studies . Also do not know if marijuana or other lifestyle factors as respondents who cause they got a number of health benefits .

One of the allegations is the influence of marijuana at specific receptors in the brain related to appetite and metabolism.

Anti- cholesterol statins , benefits and risks

Anti- cholesterol statins , benefits and risks
For controlling high cholesterol levels , medical experts commonly used drugs called statins . However, a number of studies have shown the association of statin use with the risk of diabetes mellitus (DM) .

Head of the Division of Endocrinology and Metabolism Department of Internal Medicine Dr. Cipto Mangunkusumo Hospital ( RSCM ) dr Em Yunir , SPPD KEMD said risk DM is in the class of statins in some patients do discontinue use. And he said , stopping treatment can be fatal because it will make the cholesterol increase again .

High cholesterol , particularly "bad" cholesterol or low density lipoprotein (LDL ) is a risk factor for cardiovascular disease. If it is not controlled , LDL make a plaque in the blood vessels of the bloodstream long block that makes blood vessels vulnerable to rupture.

The rupture of blood vessels can lead to disability and death. If a ruptured blood vessel in the brain is the impact of stroke. As if it occurs in the blood vessels of the heart , blood vessels may break cause disturbances of cardiac function in heart failure.

Statins are a class of drugs that lower cholesterol to operate and maintain the stability of a blockage in the blood vessels. If the consumption of drugs called statins are stopped, then again an increase in cholesterol levels and increase the risk of cardiovascular disease.

According Yunir , the benefits of statins outweigh the disadvantages . "Therefore, statin users should not stop using it , " he advised when met on Wednesday ( 11/09/2013 ) in Jakarta.

Yunir said, binding studies with statins DM showed no causal link . Instead , the study focused only on a survey of tens of thousands of people who were followed for 10 years. The result was an increase in the prevalence of diabetes among participants in statin users .

" But the study does not take into account other risk factors that play a role, such as smoking, physical activity, and others," he said .

Other studies added Yunir showed statin cessation indicate a higher than continue to take mortality. Most deaths caused by cardiovascular disease.

"In addition, even if it is exposed to DM patients on statins are also able to manage their diabetes with a blood sugar-lowering drug. Both treatments will not cause any adverse interactions ," he said .

On another occasion , Dr. Dyah Purnamasari , SPPD Endocrine Metabolism Division , Department of Internal Medicine RSCM said , cholesterol and diabetes is a collection of diseases that occur together .

When a person has diabetes , he said, in general cholesterol . This is because people with diabetes are more likely to have trouble cholesterol disorders of fat metabolism in the body.

Vice versa, if the high cholesterol , it must be searched and screened for DM . " The incidence of diabetes among users of cholesterol-lowering drugs ( statins) has also not escaped on the subject are also risk factors for diabetes," he said .

However, Dyah agreed with the benefits of statins are still much higher than the risks.

"nice" Without drugs, headaches disappear

"nice" Without drugs, headaches disappear
Some types of non-drug treatments, such as exercise , relaxation exercises , acupuncture can provide relief to long-term tension -type headaches with veins ( tension headaches ) .

Termination important analgesic treatment as a first step for tension headaches because of the frequent use of analgesics uric can actually cause headaches become chronic .

So , Dr. Elisabeth Soderberg with the team at Sahlgrenska Academy , University of Gothenburg , Sweden, presented the results of his research in the journal Cephalalgia .

In the study, the research team asked 90 random patients who had an average of seven years of experience headaches tight muscles , to follow a training exercise, relaxation , or acupuncture. Researchers classify chronic tension headaches vein when the pain lasts at least 15 days per month and six consecutive months.

During the four weeks prior to treatment, patient characteristics were assigned noted that they had experienced headaches. The recording was continued for four weeks of training and continued until the three and six months after treatment .

The use of acupuncture in the recommended 10 to 12 needles, 30 minutes per week for 10 to 12 weeks points. Directed exercise the muscles of the shoulder and neck , each for 100 times , and coupled with the ergonomic pedaling and stretching.

Although relaxation exercises include breathing exercises , techniques for stress management , and how to be relaxed during exercise and in everyday life .

The result compared to previous treatments , relaxation exercises and acupuncture significantly reduced the intensity of headaches up to three to six months. While physical exercise reduces the intensity of headaches and even release some patients for up to six months. Soderberg and the team says , the best results can be achieved with a combination of three techniques.

ALREADY FOUND, VIRUS BUSTERS CANCER CELLS

already found, Virus Busters Cancer Cells



Research to find a cure for cancer continues to be done by experts from around the world. Now present a speck of hope for cancer patients after the discovery of a single type of virus by scientists in Europe.

In its latest study , researchers from the life - Faculty of Life Sciences , University of Copenhagen in Denmark found that the vesicular stomatitis virus (VSV ) has great potential not already well known . The virus has two large capacity that is, to kill cancer cells while inhibiting the expression of specific molecules of the type of cancer cells that are hidden on the immune system.

According to the researchers , some types of cancer cells are known to express both liquid immunostimulatory molecules , blocking the immune system's ability to recognize and allow these cells progress to cancer

Vesicular stomatitis virus (VSV ) is a rhabdovirus . This virus comes from the same family with the rabies virus , and causes a disease similar to foot and mouth disease in cattle.

" The overexpression seen in cancer types such as melanoma , testicular cancer , ovarian cancer and certain types of leukemia significantly impairs the immune system, thus reducing the chances of recovery of the patient ," Soren Skov , Associate Professor of immunology LIFE.

Skov was the leader of a research team that has just launched a major EU project to study the potential to improve the treatment of cancer by strengthening the immune system. As part of his research is published in the Journal of Virology, the researchers infected human cancer cells with VSV .

" We have shown that the virus (VSV ) to kill cancer cells The results also show that VSV is very effective in inhibiting the production of immunostimulatory molecules - . Acting destroys the immune system, and thus allow a person to survive , "says Skov .

breakthrough

Skov evaluate these results as a clear breakthrough and a huge leap towards better cancer treatment, in which the immune system will be able to stop the development of cancer more effectively. Skov find hope in the future this may be an alternative to chemotherapy, tailored to each patient 's disease .

"The next step will be clinical trials in humans. Tests were conducted in the United States , "says Helle Jensen, a researcher who has conducted research in the LIFE project in collaboration with the Faculty of Health Sciences at the University of Copenhagen and the National Veterinary Institute in the technical University of Denmark (DTU ) .

DO YOU KNOW? POTENTIAL CANCER MEDICINE ZALTRAP OVERCOME DIABETES

Potential cancer medicine Zaltrap Overcome Diabetes


In addition to being used for the treatment of cancer, drug Zaltrap ( aflibercept ) is also potentially be benefits to cope with diabetes , according to a new study published in the journal Nature Medicine.

Researchers say they have identified a molecular pathway or a series of interactions between proteins involved in the progression of diabetes . And it turns out , the track can be adjusted by the Zaltrap drug against cancer.

Zaltrap is a drug that has been approved in the United States and several other countries to treat advanced colorectal cancer and macular degeneration of the wet type . This drug can inhibit the vascular vessel endothelial growth factor (VEGF ), which blocks the growth of blood vessels in the tumor cells . This is what makes the cells become starved of oxygen and eventually die .

Once identified, the researchers found there are some series that connects the VEGF inhibitor protein and sugar levels in the blood.

Study researchers, Amato Giaccia , professor of cancer biology and director of radiation oncology at Stanford University School of Medicine said, proteins involved in this pathway can be used as a target for the development of a new treatment treatment of diabetes.

" We were surprised by the finding that a drug commonly used for cancer was found to have beneficial effects on diebetes ," said another researcher , Dr. Calvin Kuo, professor of medicine at the same university.

However, he added , this study was conducted in mice and often failed the test in humans. Therefore, more research is needed to confirm this.

The researchers say , VEGF inhibitors indicated that Zaltrap can affect blood sugar levels in the blood, but there is no evidence in research on humans.