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Antibiotics can trigger asthma cases

The use of antibiotics is not fair was not only trigger the resistance of germs to antibiotics , but it also has the potential to increase the incidence and severity of allergic asthma at an early age . Thus, the results of research conducted by experts from the University of British Columbia.

This finding was published today in the journal EMBO Reports. In his study, the researchers found that the use of certain antibiotics can kill bacteria in the gut that can trigger the development of asthma.

" It has long been known that many children who are frequently exposed to antibiotics - as is the case in some developed countries - so they are more vulnerable to asthma," said researcher Brett Finlay, a microbiologist at the University of British Columbia.

"Our study is the first experimental evidence that shows how exposure to antibiotics can lead to the onset of asthma ," he added .

In his research, Finlay and his team examined how the effects of the use of two types of widely used antibiotics such as streptomycin and vancomycin can affect bacteria in the intestinal ecosystem. Finlay found that vancomycin can change the bacterial community in the gut and increase the severity of asthma ( results of experiments on rats).

Although the use of antibiotics in the same mice did not affect the adult mouse sensitivity to asthma . This suggests that life is a critical period early in the construction of a healthy immune system .

The researchers noted , asthma affects more than 100 million people worldwide and its prevalence is increasing by an average of 50 percent per decade , particularly among children in industrialized countries.

Finlay said in the intestines of humans , there are about 100000000000000 bacteria, and contains more than 1,000 species of bacteria. "Although not fully understood, but micro -organisms , which are known as" gut flora " perform a number of functions that is particularly useful for humans ," said Finlay.

"The practice of modern social, such as improved methods of sanitation and the widespread use of antibiotics , said that the cause of the disappearance of species of good bacteria in our gut may be important for healthy immune system , "said Finlay.

Finlay reiterated give antibiotics to children may be able to disrupt the normal life of the bacterium , which should not be underestimated.

The study was funded by the Canadian Institutes of Health Research (CIHR) . Marc Ouellette , Scientific Director of CIHR revealed , " was recognized that microbes play an important role in human health - and we found that disruption of the bacteria has been associated with several chronic health problems .

An important outcome of the team of Professor Finlay confirmed that " the administration of antibiotics for young children, disrupting the normal bacterial flora, should not be taken lightly . "

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